Research Programs

Brain Tumor Center of Excellence for Research

 

 

Brain tumors are the biggest cancer killer in children. Brain tumors account for 85% to 90% of all primary CNS tumors. According to the Lebanese National Cancer Registry, the incidence rate per 100,000 (ASR) is 6.9 in males and 4.4 in females. Brain tumors also reduce life expectancy by an average of 20 years, the highest of any cancer. The 5-year -survival rate for people with brain or CNS tumors is 34% for men and 36% for women. However, survival rates vary greatly depending on various factors, such as the type of brain or spinal cord tumor.

The need for a brain tumor center of excellence for research at AUBMC emerged; it aims towards being the leading center for research and personalized brain cancer treatment through multidisciplinary and collaborative research. This would contribute to better management of brain tumors with potentially significant benefits to many patients.

Our mission is to improve the quality of life and enhance the survival rates of brain cancer patients by promoting novel means of personalized targeted therapy and to fill a critical gap in brain tumor patient care and to ensure patients have the necessary information to deliver optimal patient care.

Our Goals:

  1. Provide consistent and evidence-based care for brain tumor patients
  2. Find novel medications and technologies to enhance survival rates and improve quality of life
  3. Invest in forward-thinking, outcomes-oriented and patient-focused research
  4. Providing information and support to navigate the system
  5. Make sure every patient is able to contribute to research and clinical trials.

 

Ongoing brain malignancies research projects include:

 

Brain and Central nervous system

Correlation Of O6-methylguanine Methyltransferase (MGMT) Promoter Methylation and Isocitrate Dehydrogenase 1 (IDH1) mutation With Clinical Outcomes In Patients With Glioblastoma in the Middle East: A Retrospective Cohort Study

Methodology: Translational research

PI: Hazem Assi

 

Correlation of genetic alterations by whole-exome sequencing with clinical outcomes of glioblastoma patients: a retrospective cohort study

Methodology: Translational research

PI: Hazem Assi

 

Demographics and Outcomes of Meningioma Patients Treated in a Tertiary Care Center in the Middle East

 

Second generation sequencing for Glioblastoma Multiforme

 

Leptomeningeal Carcinomatosis in Solid Tumors: Outcome and prognostic factors

 

Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Isocitrate Dehydrogenase 1 (IDH1) Mutation with Clinical Outcomes in Patients with Glioblastoma in the Middle East: A Retrospective Cohort Study??

 

Correlation of Genetic Alterations by Whole-Exome Sequencing with Clinical Outcomes of Glioblastoma Patients: a Retrospective Cohort Study

 

Epidemiology, Prognosis, and Outcomes of Schwannoma patients; a Single Institution Experience using Two Different Surgical Techniques

 

Management of Leptomeningeal Metastasis in Breast Cancer

 

EGFR as a Clinical Marker in Glioblastomas and Other Gliomas

 

Therapeutic Interventions in Adult Low Grade Glioma

 

Correlation Of O6-methylguanine Methyltransferase (MGMT) Promoter Methylation and Isocitrate Dehydrogenase 1 (IDH1) mutation With Clinical Outcomes In Patients With Glioblastoma in the Middle East: A Prospective Cohort Study?